The DSG1 Antibody (Center) from MyBioSource.com is a Rabbit Polyclonal antibody to Desmoglein 1, DG1, DSG, DSG1, and PPKS1. This antibody recognizes Human antigen. The DSG1 Antibody (Center) has been validated for the following applications: ELISA, Immunohistochemistry, and Western Blot.
Description
Desmosomes are cell-cell junctions between epithelial,
myocardial and certain other cell types. Desmoglein 1 is a
calcium-binding transmembrane glycoprotein component of desmosomes
in vertebrate epithelial cells. Currently, three desmoglein
subfamily members have been identified and all are members of the
cadherin cell adhesion molecule superfamily. These desmoglein gene
family members are located in a cluster on chromosome 18. The
protein encoded by this gene has been identified as the autoantigen
of the autoimmune skin blistering disease pemphigus foliaceus